Browsing Internal Medicine by Author "Rwegerera, Godfrey Mutashambara"
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Alanine transaminase and hemoglobin appear to predict the occurrence of antituberculosis medication hepatotoxicity; findings and implications in Botswana
Kesenogile, Boikobo; Godman, Brian; Rwegerera, Godfrey Mutashambara (Taylor & Francis. www.tandfonline.com, 2020-12-01)Objective: Tuberculosis (TB) remains a global health problem, with medications having adverse effects including drug-induced hepatotoxicity. We determined the prevalence of anti-tuberculosis drug-induced hepatotoxicity and ... -
Antidiabetic medication adherence and associated factors among patients in Botswana; implications for the future
Rwegerera, Godfrey Mutashambara; Moshomo, Thato; Gaenamong, Marea; Oyewo, Taibat Aderonke; Gollakota, Sivasomnath; Mhimbira, Francis Apolinary; Fadare, Joseph; Godman, Brian; Meyer, Johanna C.; Rivera, Yordanka Piña (Elsevier; https://www.elsevier.com/, 2017-03-06)Background: Diabetes mellitus (DM) is a major global public health problem. Lack of adherence to medication causes suboptimal glycemic control increasing complication rates, costs and mortality. The objective of the study ... -
Antimicrobial utilization research and activities in Botswana, the past, present and the future
Tiroyakgosi, Celda; Matome, Matshediso; Kgatlwane, Joyce; Paramadhas, Bene D Anand; Malone, Brighid; Mpinda-Joseph, Pinkie; Rwegerera, Godfrey Mutashambara; Maika, Keamogetse; Mashalla, Yohana; Godman, Brian; Maselle, Amos (Taylor & Francis, www.tandfonline.com, 2019-09-23)A number of activities are ongoing to reduce AMR in Botswana by improving antimicrobial utilization across all sectors. However, there is a need to share experiences. With the objective of sharing these, the second one ... -
Determinants of comprehensive knowledge of mother to child transmission (MTCT) of HIV and its prevention among Zimbabwean women: Analysis of 2015 Zimbabwe Demographic and Health Survey
Rwegerera, Godfrey Mutashambara; Masaka, Anthony; Dikeleko, Paphani; Moleta, Keletso; Morongwa, David; Kaisara, Tshephang; Rampheletswe, Fredah (Taylor & Francis; https://www.taylorfrancis.com/, 2019-09-29)Introduction: The global burden of human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome has significantly decreased; however, new HIV infections decline slowly; this poses challenges to achieve ... -
Disseminated Burkitt’s Lymphoma with a Pancreatic Mass in a HIV Positive Woman Diagnosed by Axillary Lymph Node Biopsy
Rwegerera, Godfrey Mutashambara; Rivera, Yordanka Piña; Zhou, Feng; Chobanga, Kudra Jumanne; Sesay, Sheikh Omar (Journal of Clinical and Diagnostic Research, http://www.jcdr.net/, 2017-08-01)Burkitt’s Lymphoma (BL) is a highly aggressive B cell lymphoma of non Hodgkin’s type usually presenting in extranodal sites for endemic and sporadic types of the disease. Like other Non-Hodgkin’s Lymphomas (NHL), HIV ... -
Dolutegravir induced sub-acute hepatic failure in HIV positive treatment naïve man in Botswana
Rwegerera, Godfrey Mutashambara; Rimbi, Munashe; Mudhina, Vimbai; Simone, Marang Tiny; Sefo, Moranodi; Segona, Bofelo (Sciedu Press, www.sciedupress.com, 2019-09-24)Dolutegravir associated hepatic failure has rarely been reported. Hepatic failure can occur either acutely or after few weeks as it happened in our patient. We report a case of 61 years old HIV-positive treatment naïve ... -
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: update from the GBD 2019 Study
Roth, Gregory A.; Mensah, George; Johnson, Catherine; Addolorato, Giovanni; Ammirati, Enrico; Baddour, Larry M.; GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing Group; Rwegerera, Godfrey Mutashambara (Elsevier, www.elsevier.com, 2020-12-11)Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD ... -
Health-related quality of life and associated factors among patients with diabetes mellitus in Botswana
Rwegerera, Godfrey Mutashambara; Moshomo, Thato; Gaenamong, Marea; Oyewo, Taibat Aderonke; Gollakota, Sivasomnath; Rivera, Yordanka Piña; Masaka, Anthony; Godman, Brian; Shimwela, Meshack; Habte, Dereje (Elsevier, www.elsevier.com, 2017-06-09)Background: Health-related quality of life (HRQOL) is an important aspect of diabetes mellitus care. The objective of the study was to determine the HRQOL of diabetes mellitus (DM) patients in Botswana as little known in ... -
Leydig cell tumor of the testis presenting with gynaecomastia due to hyperprolactinemia after orchiectomy
Rivera, Yordanka Pina; Rwegerera, Godfrey Mutashambara; Chowdhury, Wahhab; Chobanga, Kudra Jumanne; Milan, Alexei Ortiz (Sciedu Press, http://web.sciedu.ca/, 2017-10-10)Leydig cell tumors (LCT) are rare and represent 1% to 3% of all tumors of the testis. LCTs can either be benign or malignant with clinical presentation varying from testicular mass associated with endocrinal manifestations ... -
Metabolic control and determinants among HIV-infected Type 2 diabetes mellitus patients attending a tertiary llinic in Botswana
Rwegerera, Godfrey Mutashambara; Shailemo, Dorothea H.P.; Pina Rivera, Yordanka; Mokgosi, Kathryn O.; Bale, Portia; Oyewo, Taibat Aderonke; Diaz Luis, Bruno; Habte, Dereje; Godman, Brian (Dove Medical Press Ltd, www.dovepress.com, 2021-01-11)Purpose: We primarily aimed at determining the prevalence of metabolic syndrome and abnormal individual metabolic control variables in HIV-infected participants as compared to HIV-uninfected participants given current ... -
Non-communicable diseases in antiretroviral therapy recipients in Kagera Tanzania: a cross-sectional study
Magafu, Mgaywa Gilbert Mjungu Damas; Moji, Kazuhiko; Igumbor, Ehimario Uche; Magafu, Naoko Shimizu; Mwandri, Michael; Mwita, Julius Chacha; Habte, Dereje; Rwegerera, Godfrey Mutashambara; Hashizume, Masahiro (African Field Epidemiology Network (AFENET); www.afenet.net/, 2013-11-06)Introduction: The aim of this study was to describe the extent of self-reported non-communicable diseases (NCDs) among highly active antiretroviral therapy (HAART) recipients in Kagera region in Tanzania and their effect ... -
Prevalence and risk Factors for hepatitis B and C among end‑stage renal disease patients on hemodialysis in Gaborone, Botswana
Mahupe, Ponatshego; Molefe-Baikai, Onkabetse Julia; Saleshando, Gagoitsiwe; Rwegerera, Godfrey Mutashambara (Medknow Publishers, www.medknow.com, 2021-01)Background: Patients on maintenance hemodialysis (HD) are at risk of blood transmitted infections such as hepatitis B and C. Objectives: To determine the prevalence and risk factors for hepatitis B and hepatitis C virus ... -
Response to the novel Corona virus (COVID-19) pandemic across Africa: successes, challenges, and implications for the Future
Ogunleye, Olayinka O.; Basu, Debashis; Mueller, Debjani; Sneddon, Jacqueline; Seaton, R. Andrew; Yinka-Ogunleye, Adesola F.; Wamboga, Joshua; Miljković, Nenad; Mwita, Julius C.; Rwegerera, Godfrey Mutashambara (Frontiers Media S.A., www.frontiersin.org, 2020-09-11)Background: The COVID-19 pandemic has already claimed considerable lives. There are major concerns in Africa due to existing high prevalence rates for both infectious and non-infectious diseases and limited resources in ... -
Review of ongoing activities and challenges to improve the care of patients with Type 2 Diabetes across Africa and the implications for the future
Godman, Brian; Basu, Debashis; Pillay, Yogan; Mwita, Julius C.; Rwegerera, Godfrey Mutashambara; Paramadhas, Bene D. Anand; Tiroyakgosi, Celda; Okwen, Patrick Mbah; Niba, Loveline Lum; Nonvignon, Justice; Sefah, Israel; Oluka, Margaret; Guantai, Anastasia N. (Frontiers Media S.A. www.frontiersin.org, 2020-03-20)Background: There has been an appreciable increase in the number of people in Africa with metabolic syndrome and Type 2 diabetes (T2DM) in recent years as a result of a number of factors. Factors include lifestyle changes, ... -
Salmonella sepsis and urinary tract infection complicating with acute kidney injury in a HIV positive female patient
Rwegerera, Godfrey Mutashambara; Ramolefhe, Thato Tumediso; Ngoy, Ngoy Alphonse; Lesiamang, Molatedi; Pina Rivera, Yordanka (Journal of Clinical and Diagnostic Research; https://www.jcdr.org.in/, 2019-03-01)Urinary Tract Infection (UTI) can rarely be caused by salmonella species. UTI salmonellosis may present as uncomplicated UTI, pyelonephritis or haemorrhagic cystitis. We present a case of a 44-year-old HIV positive female ... -
Short stature and growth hormone deficiency: unexpected manifestations of McCune-Albright syndrome
Pina Rivera, Yordanka; Rwegerera, Godfrey Mutashambara; Sesay, Sheikh (BMJ Publishing Group Limited; https://www.bmj.com/, 2018-08-27)McCune-Albright syndrome (MAS) is a rare disease characterised by triad of monostotic or polyostotic fibrous dysplasia, café au-lait skin spots and a variety of endocrine disorders; precocious puberty (PP) being the most ...