Please use this identifier to cite or link to this item: http://hdl.handle.net/10311/1929
Full metadata record
DC FieldValueLanguage
dc.contributor.authorTsima, Billy-
dc.contributor.authorRatcliffe, Sarah Jane-
dc.contributor.authorSchnoll, Robert-
dc.contributor.authorFrank, Ian-
dc.contributor.authorKolson, Dennis Larry-
dc.contributor.authorGross, Robert-
dc.date.accessioned2019-05-08T12:53:39Z-
dc.date.available2019-05-08T12:53:39Z-
dc.date.issued2018-
dc.identifier.citationTsima, B. et al (2018) Is tobacco use associated with neurocognitive dysfunction in individuals with HIV? Journal of the International Association of Providers of AIDS Care, Vol. 17, pp. 1-7en_US
dc.identifier.issn2325-9582-
dc.identifier.urihttp://hdl.handle.net/10311/1929-
dc.description.abstractIntroduction: The prevalence of HIV-associated neurocognitive disorders continues to rise despite the widespread use of antiretroviral therapy. We aimed to define the risk of neurocognitive dysfunction among smokers relative to nonsmokers. Methods: We conducted a retrospective cohort study including HIV-infected adults ages 21 to 65 years. The Mental Alternation Test (MAT) was the primary outcome. The odds of cognitive impairment were compared using random-effects logistic regression to adjust for potential confounders. Results: Of 3033, 1486 (49%) were smokers. The odds ratio for the association between smoking and cognitive impairment was 1.12 (95% confidence interval: 0.85-1.49). Nonsmokers had a higher median MAT score relative to smokers (P ¼ .01). Conclusion: There was no evidence that HIV-infected smokers had greater neurocognitive dysfunction relative to HIV-infected nonsmokers. While tobacco use remains an important health risk issue to address in the HIV population, it may not represent a risk factor for neurocognitive impairment.en_US
dc.language.isoenen_US
dc.publisherSage publications, www.sage.com/‎en_US
dc.subjectHIV-1en_US
dc.subjectHANDen_US
dc.subjectsmokingen_US
dc.subjecttobaccoen_US
dc.subjectneurocognitive dysfunctionen_US
dc.titleIs tobacco use associated with neurocognitive dysfunction in individuals with HIV?en_US
dc.typePublished Articleen_US
dc.linkis_tobacco_use_associated_with_neurocognitive_dysf.pdf-adope acrobat reader dcen_US
Appears in Collections:Research articles (School of Medicine)

Files in This Item:
File Description SizeFormat 
Tsima_JIAPAC_2018.pdf168.61 kBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.