Phenolic and antibacterial constituents of Vahlia capensis

Please use this identifier to cite or link to this item: http://hdl.handle.net/10311/1938

Title:	Phenolic and antibacterial constituents of Vahlia capensis
Authors:	Majinda, Runner R.T. Motswaledi, Modisa Waigh, Roger D. Waterman, Peter G.
Issue Date:	1997
Publisher:	Georg Thieme Verlag, https://www.thieme.com/books-main/biochemistry/product/3494-planta-medica
Citation:	Majinda, R.R.T. et al. (1997) Phenolic and antibacterial constituents of Vahlia capensis. Planta Medica, Vol. 63, No. 3, pp. 268-270
Abstract:	The n-butanol fraction of Vahlia capensis yielded kaempferol, quercetin, afzelin, astragalin, quercitrin, iso-quercitrin, rutin, gallic acid, chiro-inositol, dulcitol, and a novel biflavonoid, VC-15B (vahlia biflavone). The compounds were identified using ID and 2D NMR techniques and FABMS. Vahlia biflavone and gallic acid were isolated, using bioassay-guided procedure and identified as the antibacterial components. Both compounds showed activity against Gram positive Staphylococcus aureus and Bacillus subtilis. Vahlia biflavone gave MIC values of 15.3 µg/ml and 30.6 µg/ml against S. aureus and B. subtilis, respectively while gallic acid gave a value of 71.3 µg/ml for both organisms.
Description:	NB: Some symbols may not appear as they are on the original document.
URI:	http://hdl.handle.net/10311/1938
ISSN:	0032-0943
Appears in Collections:	Research articles (Dept of Chemistry)

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