Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima

Please use this identifier to cite or link to this item: http://hdl.handle.net/10311/216

Title:	Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima
Authors:	Chacha, M. Bojase-Moleta, G. Majinda, R.R.T.
Keywords:	Erythrina latissima Fabaceae-Papilionoideae Isoflavones Flavanone Antibacterial Antifungal activity Radical scavenging properties
Issue Date:	20-Nov-2004
Publisher:	Elsevier Ltd; http://www.elsevier.com/wps/find/journaldescription.cws_home/273/description
Citation:	Chacha, M. et al (2004) Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima, Phytochemistry, Vol. 66, No. 1, pp. 99-104
Abstract:	From the stem wood of Erythrina latissima, two isoflavones and a flavanone were isolated and characterized as 7,3'-dihydroxy-4'-methoxy-5'-(y,y-dimethylallyl)isoflavone (erylatissin A), 7,3'-dihydroxy-6".6"-dimethyl-4".5"-dehydropyrano [2",3":4'.5']isoflavone (erylatissin B), (-)-7,3'-dihydroxy-4'-methoxy-5'-(y,y-dimethylallyl)flavanone (erylatissin C), respectively, in addition to 10 known flavonoids. Structures of these compounds were determined on the basis of their spectroscopic data. These compounds showed antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Candida mycoderma. The isolated compounds also exhibited weak radical scavenging properties towards DPPH radical.
URI:	http://hdl.handle.net/10311/216
ISSN:	0031-9422
Appears in Collections:	Research articles (Dept of Chemistry)

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