Now showing items 1-2 of 2

  • Screening of the pan-African Natural Product Library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors 

    Tietjen, Ian; Ntie-Kang, Fidele; Mwimanzi, Philip; Onguéné, Pascal Amoa; Scull, Margaret A.; Idowu, Thomas Oyebode; Ogundaini, Abiodun Oguntuga; Meva’a, Luc Mbaze; Abegaz, Berhanu M.; Rice, Charles M.; Andrae-Marobela, Kerstin; Brockman, Mark A.; Brumme, Zabrina L.; Fedida, David (Public Library of Science,, 2015)
    The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to existing antiretroviral therapies, emphasize the need to ...
  • Virtualizing the p-ANAPL library: A step towards drug discovery from African medicinal plants 

    Ntie-Kang, Fidele; Onguéné, Pascal Amoa; Fotso, Ghislain W.; Andrae-Marobela, Kerstin; Bezabih, Merhatibeb; Ndom, Jean Claude; Ngadjui, Bonaventure T.; Ogundaini, Abiodun O.; Abegaz, Berhanu M.; Meva’a, Luc Mbaze (Public Library of Science,, 2014)
    Background: Natural products play a key role in drug discovery programs, both serving as drugs and as templates for the synthesis of drugs, even though the quantities and availabilities of samples for screening are often ...